Review

ccd 1079sk (ATCC)

ATCC is a verified supplier

ATCC manufactures this product

About

News

Press Release

Team

Advisors

Partners

Contact

Bioz Stars

Bioz vStars

Buy from Supplier

Structured Review

ATCC ccd 1079sk

Evaluation of cytotoxicity of CD21chol and its complexes with 5-FU against human fibroblast cells <t>(CCD-1079Sk)</t> and cardiomyocytes (H9c2(2–1)). ( A and C ) show the proliferation of CCD-1079Sk cells and H9c2(2–1) cells after treatment with empty and 5-FU-loaded CD21chol. ( B and D ) show the viability of CCD-1079Sk cells and H9c2(2–1) cells after treatment with empty and 5-FU-loaded CD21chol. Data are presented as mean ± SD. Statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test. Statistical significance was defined as follows: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Ccd 1079sk, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 336 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ccd+1079sk/CCD-1079Sk/pmc13248979-79-11-9
Average 96 stars, based on 336 article reviews

ccd 1079sk - by Bioz Stars, 2026-10

96/100 stars

Images

1) Product Images from "Cyclodextrin-Based Nanocarriers for 5-Fluorouracil: Cholesteryl Modification Enhances Antitumor Activity Against Colorectal Cancer Cells"

Article Title: Cyclodextrin-Based Nanocarriers for 5-Fluorouracil: Cholesteryl Modification Enhances Antitumor Activity Against Colorectal Cancer Cells

Journal: International Journal of Nanomedicine

doi: 10.2147/IJN.S583792

Evaluation of cytotoxicity of CD21chol and its complexes with 5-FU against human fibroblast cells (CCD-1079Sk) and cardiomyocytes (H9c2(2–1)). ( A and C ) show the proliferation of CCD-1079Sk cells and H9c2(2–1) cells after treatment with empty and 5-FU-loaded CD21chol. ( B and D ) show the viability of CCD-1079Sk cells and H9c2(2–1) cells after treatment with empty and 5-FU-loaded CD21chol. Data are presented as mean ± SD. Statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test. Statistical significance was defined as follows: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Figure Legend Snippet: Evaluation of cytotoxicity of CD21chol and its complexes with 5-FU against human fibroblast cells (CCD-1079Sk) and cardiomyocytes (H9c2(2–1)). ( A and C ) show the proliferation of CCD-1079Sk cells and H9c2(2–1) cells after treatment with empty and 5-FU-loaded CD21chol. ( B and D ) show the viability of CCD-1079Sk cells and H9c2(2–1) cells after treatment with empty and 5-FU-loaded CD21chol. Data are presented as mean ± SD. Statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test. Statistical significance was defined as follows: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Techniques Used:

Control:

Article Title: Alternative polyadenylation alters protein dosage by switching between intronic and 3'UTR sites.
Article Snippet: We purchased three healthy control infant fibroblast lines: CCD1064Sk, CCD-1070Sk, and CCD-1079Sk (American Type Culture Collection, Manassas, VA). .. We purchased three healthy control infant fibroblast lines: CCD1064Sk, CCD-1070Sk, and CCD-1079Sk (American Type Culture Collection, Manassas, VA). ..

Multiple Displacement Amplification:

Article Title: Covalent modification of iron oxide-poly(lithocholic acid) nanoparticles with folic acid or doxorubicin – an approach for enhanced cancer therapy
Article Snippet: The cytotoxicity of polymer–inorganic hybrids based on iron oxide nanoparticles comprising poly(lithocholic acid acrylate) or poly(acrylic acid) blocks and their modification by FA and DOX was determined against skin fibroblast CCD-1079sk, cardiomyocytes cells H9C2, breast cancer cells (MCF-7 and MDA-MB-231), and cervical cancer cells HeLa from American Type Culture Collection (Manassas, VA, USA). .. The cells were cultivated in 96-well plates at a density of 5–7 × 10 3 cells per well until they reached full confluence in Eagle's Minimum Essential Medium-EMEM (ATCC) (for CCD-1079sk, HepG2, MCF-7, MDA-MB-231, HeLa), and in Dulbecco's modified Eagle's Medium-DMEM (ATCC) for H9c2(2-1) supplemented with 10% fetal bovine serum (FBS) (ATCC), 50 U mL −1 penicillin, and 50 mg mL −1 streptomycin (Gibco, Thermo Fisher Scientific, Inc., Waltham, MA, USA) under physiological conditions, at 37 °C with 5% CO 2 . ..

Modification:

Article Title: Targeted delivery of doxorubicin via cholesteryl-modified cyclodextrin: Antitumor activity in breast, ovarian, and cervical cancer cell lines.
Article Snippet: High cytotoxicity towards physiological cells and the development of drug resistance remain major challenges in anticancer therapy.. The use of drug delivery systems for doxorubicin hydrochloride (DOX⋅HCl) aims to enhance its selective accumulation in cancer cells and reduce adverse effects on normal tissues.. In this study, complexation efficiency was assessed through spectroscopic analysis and computational chemistry methods, while cytotoxicity was evaluated using in vitro assays on selected cell lines, including normal cells (CCd1079Sk) and cancerous cells (MCF-7, HeLa, and SKOV-3).

Article Title: Cyclodextrin-Based Nanocarriers for 5-Fluorouracil: Cholesteryl Modification Enhances Antitumor Activity Against Colorectal Cancer Cells
Article Snippet: .. Cells were cultured in Eagle’s Minimum Essential Medium (EMEM, ATCC) (for CCD-1079Sk) or in Dulbecco Modified Eagle Medium (DMEM) (for DLD-1 and H9c2(2–1)) supplemented with 10% FBS (Gibco) and 1% antibiotic (Penicillin-Streptomycin, 10,000 U·mL −1 , Gibco) in an incubator set at 37 °C in a 5% CO 2 atmosphere. .. After 24 hours, the cells were washed with warm phosphate-buffered saline (PBS, CORNING) and then trypsinized with warm trypsin-EDTA (0.25%, Gibco) to detach them from the medium before being seeded into 96-well plates.

Cell Culture:

Article Title: Remote-controlled release of therapeutics from multifunctional glycoplexes inhibit melanoma cells
Article Snippet: Delivery system-based phototherapies such as photodynamic therapy (PDT) and photoactivated chemotherapy have been widely used for curative and palliative cancer treatment due to their selectivity and remote controllability.. In this study, biocompatible glycopeptide based multifunctional nanoplexes were fabricated for targeted PDT-chemo-/gene therapy of melanoma.. Multifunctional protoporphyrin IX (PpIX)-conjugated polymers were synthesized by reversible addition–fragmentation chain transfer polymerization and ring-opening polymerization from glucose transporter (GLUT1) targeted sugar (glucose/mannose) or non-targeted OEGMEMA monomers, pH-responsive lysine monomer, and pH/singlet oxygen-responsive imidazole functionalized glutamate monomer.

other:

Article Title: Post-transcriptional splicing can occur in a slow-moving zone around the gene
Article Snippet: Cell line ( Homo sapiens ) , CRL-2097 , ATCC , CCD-1079Sk , .

Similar Products

Image Search Results

Journal: International Journal of Nanomedicine

Article Title: Cyclodextrin-Based Nanocarriers for 5-Fluorouracil: Cholesteryl Modification Enhances Antitumor Activity Against Colorectal Cancer Cells

doi: 10.2147/IJN.S583792

Figure Lengend Snippet: Evaluation of cytotoxicity of CD21chol and its complexes with 5-FU against human fibroblast cells (CCD-1079Sk) and cardiomyocytes (H9c2(2–1)). ( A and C ) show the proliferation of CCD-1079Sk cells and H9c2(2–1) cells after treatment with empty and 5-FU-loaded CD21chol. ( B and D ) show the viability of CCD-1079Sk cells and H9c2(2–1) cells after treatment with empty and 5-FU-loaded CD21chol. Data are presented as mean ± SD. Statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test. Statistical significance was defined as follows: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Article Snippet: Cells were cultured in Eagle’s Minimum Essential Medium (EMEM, ATCC) (for CCD-1079Sk) or in Dulbecco Modified Eagle Medium (DMEM) (for DLD-1 and H9c2(2–1)) supplemented with 10% FBS (Gibco) and 1% antibiotic (Penicillin-Streptomycin, 10,000 U·mL −1 , Gibco) in an incubator set at 37 °C in a 5% CO 2 atmosphere.

Techniques:

$Proposed schematic representation of the multi-target protective mechanisms of Que against UVA-induced skin photoaging. Chronic UVA irradiation (320–400 nm) triggers the excessive production of reactive oxygen species (ROS) in dermal fibroblasts. These ROS subsequently activate diverse pathological cascades, primarily the NF-$\kappa$B-mediated inflammatory response and the MAPK/AP-1/MMPs axis, which collectively drive extracellular matrix (ECM) breakdown and structural remodeling. Topical Que intervention facilitates a synergistic protective effect: (1) it reinforces the antioxidant defense by promoting NRF2/SOD2 activation to neutralize ROS; and (2) it concurrently dampens the pro-inflammatory and proteolytic signals by inhibiting the NF-κB and MAPK/AP-1 pathways. This integrated modulation reestablishes cutaneous redox and inflammatory homeostasis, ultimately alleviating dermal degradation and the photoaging phenotype. Symbols: Green arrows = activation; red arrows = induction of pathological cascades; red T-bars = inhibition; “ROS↓” = reduced ROS levels.$

Journal: Pharmaceuticals

Article Title: Quercetin Emulsion Ameliorates UVA-Induced Skin via Modulation of NRF2/NF-κB Signaling Pathways

doi: 10.3390/ph19050746

Figure Lengend Snippet: Proposed schematic representation of the multi-target protective mechanisms of Que against UVA-induced skin photoaging. Chronic UVA irradiation (320–400 nm) triggers the excessive production of reactive oxygen species (ROS) in dermal fibroblasts. These ROS subsequently activate diverse pathological cascades, primarily the NF-$\kappa$B-mediated inflammatory response and the MAPK/AP-1/MMPs axis, which collectively drive extracellular matrix (ECM) breakdown and structural remodeling. Topical Que intervention facilitates a synergistic protective effect: (1) it reinforces the antioxidant defense by promoting NRF2/SOD2 activation to neutralize ROS; and (2) it concurrently dampens the pro-inflammatory and proteolytic signals by inhibiting the NF-κB and MAPK/AP-1 pathways. This integrated modulation reestablishes cutaneous redox and inflammatory homeostasis, ultimately alleviating dermal degradation and the photoaging phenotype. Symbols: Green arrows = activation; red arrows = induction of pathological cascades; red T-bars = inhibition; “ROS↓” = reduced ROS levels.

Article Snippet: Human dermal fibroblasts (HDFs, ATCC, CRL-2097) were purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA) as primary cells derived from adult foreskin tissue.

Techniques: Irradiation, Activation Assay, Inhibition